Coluracetam is a new and unique member of the racetam class of synthetic nootropics. Coluracetam, or N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxo-1-pyrrolidinyl)acetamide, is a synthetic compound of the racetam family. Racetams share a pyrrolidine nucleus, a five-member nitrogenous ring with a ketone bonded oxygen at R2. This 2-pyrrolidone ring is bound to the terminal carbon of an acetamide group, an ethyl amide chain with a ketone bond (C=O) at the alpha carbon. Originally developed as a potential treatment for Alzheimer’s disease and later considered as a treatment for depression and anxiety, coluracetam has become a popular nootropic known for improving mood, increasing motivation, and enhancing vision. Coluracetam was first synthesized in 2005 by Japan’s Mitsubishi Tanabe Pharma Corporation as an Alzheimer’s disease treatment. Coluracetam is a nootropic that was derived from racetam, although very distinct from other compounds like Piracetam, & Aniracetam. Coluracetam appears to interact with a process known as high affinity choline uptake, which is the rate-limiting step of drawing choline into a neuron for synthesis into the neurotransmitter acetylcholine.
***RESEARCH USE ONLY***
*The information herein is for educational and informational purposes only. THIS PRODUCT IS FOR RESEARCH USE ONLY. For use in animal studies, all research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act (AWA).