What it is: Cardarine (GW-501516) is grouped in the category of SARMs, however in structure and definition, it is a PPAR modulator. As a PPAR modulator, it activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue. GW-501516 possesses abilities to reverse metabolism problems by stimulating fatty acid oxidation. It is considered a strong treatment for obesity and other related conditions.
FUNCTIONS: Several research studies have been conducted on rats with Cardarine (GW-501516) implementation. GW is a selective agonist, or activator, of the PPAR receptor. The binding of GW-501516 to PPAR recruits the co activator PGC-1a. The PPAR/co activator complex then up regulates the expression of proteins involved in energy expenditure.
GW-501516 has also show to increase fatty acid metabolism in skeletal muscle and protect against obesity caused from diet. Testing conducted on obese rhesus monkeys proved GW increased HDL (good cholesterol) and lowered VLDL (bad cholesterol). GW was originally intended to be created as a treatment for cholesterol problems, which it has shown to possess a high rate of efficacy in doing.
Uses and Abilities: GW-501516 possesses many strong attributes and abilities but is known for two major strengths.
The endurance benefits that can be obtained with GW-501516 research are unmatched. There is a strong reason that it has been banned in many professional sport settings, most notably, the Olympics, NCAA and with professional cyclists. GW-501516 can drastically improve endurance over extended periods of time buy expanding the VO2 max, allowing for continuous improvements in aerobic capacity. This allows for research subjects to reach potential that would otherwise be unattainable. This SARM PPAR modulator allows one to overcome plateaus and reach peak level.
GW-501516 was originally designed to treat cholesterol and this is a characteristic that should never be forgotten, yet in many circumstances, it is. Although this is an extremely strong characteristic, this is not one of the top two major strengths it is known for. This characteristic is that of fat loss. GW is extremely desirable because it has the ability to shed fat rapidly while staying in a non-catabolic state. GW gives one the ability to drop fat at a far higher rate than generally possibly, yet in an extremely safe facet.
Side effects: GW has not shown to have any side effects. There have been several studies on GW and there is always one controversial study that will continue to show. The study showed GW to possibly cause cancer in rats. These study has been refuted time and time again. The study had rats taking extreme amounts of GW for extended periods of time. Other studies dosed properly have not show any side effects to be present. GW has no toxicity, no suppression and no other know side effects. Dosing lengths generally run 8-16 weeks at 10 to 20 mg per day, 20 mg being the most common and most effective.
***SHAKE WELL BEFORE RESEARCH*** ***RESEARCH USE ONLY***
*This information here is intended for educational and informational purposes only. THIS PRODUCT IS INTENDED FOR RESEARCH USE ONLY. This allows you to do lab research with the product, it is strictly used for in vitro testing and laboratory experiments.
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